2017-01-26

Raees vs Kaabil - First Day Box Office

The battle between "Raees" and "Kaabil" was termed as the biggest clash of Bollywood in recent history. Hrithik Roshan on one side and Shah Rukh Khan on the other side - the names justify why it was called the biggest clash of Bollywood.


Raees


Both films opened on 25th January. Let's see how these films performed at the box office. I've previously written an article about Raees having an upper hand in the battle against Kaabil. You can read it below -





What are the critics saying?



Let's have a look at some review from some of the top critics.


1. This one's from Taran Adarsh.




2. This one's from Anupama Chopra






Kaabil


3. This one's from Komal Nahta





Now box-office



Critics can go to hell. The reviews from the audiences are all that matters when it comes to box-office collections. Both the films got excellent reviews from the audiences. But Raees took the opening day by storm due to the star-power while Kaabil was left far behind.


Raees maintained an occupancy of 80-90% throughout the day while Kaabil managed only 40-50% occupancy. Kaabil played better in South India while Raees was the undisputed winner everywhere else. Raees may or may not have set an opening day record in West Bengal - it can only be confirmed after the dust settles.


Now, as per Taran Adarsh, the opening-day box-office collection for Raees is -




For Kaabil, the opening-day stands at -




Conclusion



As expected, Raees took a much better opening than Kaabil due to the presence of SRK. Today, both the films will get a huge boost in the collections as today is a national holiday. The collections will depend upon "word-of-mouth" from tomorrow.

2017-01-24

Fun Fact - Turn On The Lights To Increase Your Sp*rm Count

Nowadays, the biggest problem in a man's life is infertility. People nowadays are so busy with their jobs, studies and extracurricular activities that they just neglect their reproductive lives.


Tension, junk food are affecting people's lives in ways you can't even imagine. Decreased sper* count, increased blood pressure etc are just some of the side-effects of today's busy lifestyle.


It's very humiliating for a man to have very less sper* count. But today I'm gonna tell you how to increase your sper* count.


Count


It's another article in the popular "Fun Fact" series. You can read all the articles by going to the following link -





Melatonin - The magic hormone



It is a small endocrine gland which is situated in the brain. The pineal gland secretes melatonin which modulates the "sleep-wakefulness" cycle. Darkness enhances melatonin secretion and light stimulus decreases the secretion of melatonin. Let's see how light decreases melatonin secretion -


  • "photosensitive Retinal Ganglion Cells (pRGC)" in the retina, receives light impulse and sends the relevant signals to "Suprachiasmatic nucleus (SCN)" of the hypothalamus.

  • Relevant signals are then sent to "Paraventricular nucleus (PVN)" of the hypothalamus from SCN.

  • From PVN, impulses are sent to "Superior cervical ganglia (SCG)" of the autonomic nervous system through the spinal cord and sympathetic nervous system.

  • Postganglionic axons from the SCG, innervate pineal gland and regulates its function.


Melatonin


Reproductive organs



  • The test*s is the main reproductive organ of males. The ovary is the main reproductive organ of females. Test*s secrets Testosterone and the ovaries secrete Progesterone and Oestrogen.

  • Secretion of these s*x hormones is regulated by the pituitary gland. The pituitary secretes "Follicle-stimulating hormone (FSH)" and "Luteinizing hormone (LH)." These hormones, in turn, control the secretion of the hormones secreted by "Test*s and Ovary."

  • Secretion of LH and FSH from the pituitary gland is modulated by "Gonadotropin-releasing hormone (GnRH)" which is secreted by the hypothalamus.


Releasing Hormone


Click the following link to know how releasing hormones like GnRH and inhibitory hormones like PIH affect the secretion of hormones from the pituitary gland -



How they are linked?



  • Melatonin decreases the release of GnRH from the hypothalamus. Decreased GnRH level causes decrease the secretion of LH and FSH from the pituitary gland.

  • Decreased LH and FSH, in turn, decreases the release of Testosterone, Progesterone and Oestrogen.

  • As stated above, light stimuli decrease melatonin secretion. As a result, production of s*x hormones is increased.


Count Relation


Conclusion



You can read about many amazing facts here -



See how light and darkness affects your reproductive functions? Next time, have s*x with the lights on.

2017-01-22

Know The Other Important Functions Of Kidney Besides Urine Excretion

We all know that kidney is the main excretory organ of the human body. But kidney performs several other functions besides that also. Today, I'm gonna tell in brief about those functions. I'll try not to go into fine details as that will be tough to understand and time-consuming at the same time.


Kidney


You can check other Physiology facts by going to the link below -






1. Renin - Angiotensin system (RAS)


RAS plays an important role in the regulation of blood pressure in our body.

  • Decreased Sodium concentration causes a decrease in the renal blood flow. In simpler terms, blood flow to the kidneys is reduced. This, in turn, causes a reduction in the glomerular filtration rate.

  • Such phenomenon stimulates "Juxtaglomerular cells" which in turn secrets Renin.

  • Renin causes conversion of Angiotensin to Angiotensin I. Angiotensin converting enzyme from the lungs, converts Angiotensin I into Angiotensin II. Angiotensin II causes vasoconstriction and your blood pressure increases. It also causes secretion of aldosterone.


Blood Pressure


2. Helping in the formation of red blood cells (RBC)


  • Erythropoietin is a hormone which controls Erythropoiesis or the production of RBCs. Erythropoietin (EPO) is secreted by peritubular interstitial cells of the kidney.
  • Decreased oxygen levels cause phosphorylation of "Hypoxia-inducible factor 1-alpha (HIF-1-alpha)." Then HIF-1-alpha and "aryl hydrocarbon receptor nuclear translocator" forms a heterodimeric transcription factor. This heterodimer enters causes formation of EPO-gene.
  • EPO-gene increases EPO-mRNA formation. EPO-mRNA helps in the formation of Erythropoietin.


RBC


3. Buffer system


The increase of hydrogen ion concentration in your body is termed as acidosis (Decreased pH). The increase of bases in your body is termed as alkalosis (Increased pH). Kidney maintains body pH by following four buffer systems -

  • Phosphate buffer system.

  • Bicarbonate buffer system.

  • Ammonia buffer system.

  • Weak acid buffer system.


Bicarbonate Buffer



4. Vitamin D


The active form of Vitamin D is 1,25-dihydroxycholecalciferol (1,25-DHCC). Enzyme 1-alpha-hydroxylase causes the conversion of 1,25-DHCC from 25-HCC. This particular enzyme is secreted by proximal convoluted tubule of the nephron in the kidney.


Conclusion

You can read articles from our popular "Fun Facts" series from the links below -


Need to loose some weight. Have a look here - Loose your weight in the best way possible.


Overweight


As you can see from the above data, kidney performs many important functions in our body. If you wanna know in details about these functions, feel free to leave a comment below or contact us by going here - Contact Us.

2017-01-20

Fun Fact - It Rains Diamonds On Jupiter And Saturn

It rains water on the earth. Although we've seen acid rain also. But rain full of diamonds? Yes, it actually rains diamonds on Neptune and Uranus.



Diamond


Now that I've got your attention, let's start the article. This is another article in the "Fun Facts" series where I share debunk myths and share some really cool and weird kinds of stuff. You can read other articles in this series by going to the following link -




Diamond


Diamonds are expensive but do you know what they are made up of? The answer is Carbon. Yes, the same Carbon that is present on your pencil as graphite. Are diamonds so rare? This is a myth actually. In fact, diamonds are more commonly available than other gems. Emeralds, rubies and sapphires are found in lesser amounts on the earth than diamonds.


Pencil


Let's bust another myth in this article. Are diamonds the most valuable gem? Well, this is subjective. People think that diamonds are expensive because they are so rare. But that is just not the case as I explained in the previous paragraph. They are expensive because of the much higher demand for them than other gems.


Diamonds are formed under great pressure and temperature. Under high pressure, carbon atoms form a crystalline structure called diamond lattice. Diamonds are the hardest naturally occurring material found on the earth.


Raining diamonds?


There is methane present in the atmosphere of both Jupiter and Saturn. Methane is made up of one carbon and four hydrogen atoms. Lightning converts methane into carbon. It starts in the higher atmospheric area. Carbon atoms then fall freely towards the surface of those planets.


Raining Diamonds


As they move closer to the surface, the pressure increases. They are now turned into graphite. As they become move closer and closer to the surface, the pressure increases rapidly and the graphite is now turned into a diamond. But due to high temperatures on the surface, diamonds stay in the crystalline form for a small amount of time only.


Methane is also present in the atmosphere of Neptunes and Jupiter. And because of lower temperatures on the surface of these two planets, diamonds stay in the crystalline form for a much longer amount of time.


Conclusion


Check out other articles on this blog -




Scientists have tested the above phenomenon artificially in the laboratory and they have confirmed it also. You can read about it on Wikipedia.


Just go to Neptune or Jupiter, collect those diamonds and travel back to earth. It does seem like a viable business plan. So when are you starting to build a rocket? You are planning to go to one of these planets, right?

2017-01-19

Fun Fact - Pituitary Is Not The Master Gland

The pituitary gland is often called the master gland as it controls the functions of various other endocrine glands like - Thyroid gland, Adrenal gland, Kidney etc. Well, at least we're taught to call the pituitary gland as the master gland from our school-days.


Another article in the fun fact series and once again, another lie is gonna get debunked. You can read the previous articles in the "Fun Fact" series by going to the following link -


The Pituitary gland


Pituitary
Source - A Fair Go
The pituitary gland is divided into two lobes - i) Anterior lobe, ii) Posterior lobe.

i) Anterior lobe - This lobe secretes many hormones. Some examples are -

  • Adrenocorticotrophic hormone (ACTH).
  • Luteinizing hormone (LH).
  • Prolactin (PRL).
  • Growth hormone (GH).

ii) Posterior lobe - This lobe secretes two hormones -

  • Oxytocin.
  • Vasopressin or Antidiuretic hormone (ADH).

But there are some misconceptions regarding the hormones secreted from the posterior lobe of the pituitary gland. More on that later.

Why pituitary is called the master gland?

Let's make you understood this segment by giving an example. Thyroid-stimulating hormone or TSH, secreted from the anterior lobe of the pituitary gland, acts on the Thyroid gland to stimulate the production of Tetraiodothyronine or Thyroxine (T4) and Triiodothyronine (T3). 


So, the pituitary secretes a hormone which controls the function of another gland. That's why it is called as the master gland. Like TSH, other hormones from pituitary gland such as ACTH and LH act on Adrenal Cortex and Interstitial cells of Leydig respectively.


Pituitary Gland
Source - Health Is A Journey


Revelling time now

The pituitary gland is under the control of Hypothalamus. The anterior lobe of pituitary and hypothalamus are linked by a portal system called "Hypothalamo - Hypophyseal Portal System." There are neurones called Parvocellular neurones or Parvocellular neurosecretory cells in the Hypothalamus.


These neurones secrete releasing hormones and inhibiting hormones to control the secretion of the anterior pituitary. Some examples are given below -


  • Corticotropin-releasing hormone (CRH).
  • Thyrotropin-releasing hormone (TRH).
  • Prolactin-inhibiting hormone (PIH).

The axons of Parvocellular neurones terminate on the capillary network of Hypothalamo - Hypophyseal Portal System in the median eminence of Hypothalamus. So the above hormones reach the anterior pituitary via the portal system. CRH and TRH control the secretion of ACTH and TSH from the anterior pituitary respectively.

Portal System
Source - Bioninja

Magnocellular neurones of the hypothalamus secrete Oxytocin and Vasopressin. These hormones are then carried to the posterior pituitary. Only then the posterior pituitary can secrete ADH and Oxytocin into the blood.

Conclusion

You can read other articles in the fun facts series by going to the following links -

As you can see, hormones from the hypothalamus control the secretions of hormones from the pituitary gland. Are you still gonna call the pituitary gland as the master gland?